异位妊娠患者使用甲氨喋呤和米非司酮的效果探讨

Patients with ectopic pregnancy with methotrexate and mifepristone effect is discussed in this paper

目的:观察米非司酮联合甲氨喋呤治疗异位妊娠的临床疗效。方法:将20例异位妊娠患者随机分为治疗组和观察组各10例。治疗组采用甲氨喋呤联合米非司酮治疗,对照组单用甲氨喋呤。观察两组治愈率及药物副反应。结果:治疗组的治愈率为90%显著高于对照组的70%,差异显著,而在药物不良反应方面,组间差异无统计学意义(P>0.05)。结论:甲氨喋呤联合米非司酮治疗异位妊娠的临床疗效明显优于单用甲氨喋呤,值得推广应用。

Objective to observe mifepristone combined methotrexate for the treatment of ectopic pregnancy clinical curative effect.Methods 20 patients with ectopic pregnancy were randomly divided into treatment group and observation group （n = 10.Treatment group using methotrexate combined therapy with mifepristone and methotrexate alone in the control group.Observe two groups of the cure rate and drug side effects.Results the treatment group cure rate was 90% in the control group is significantly higher than 70%, significant difference, but in terms of adverse drug reactions, there was no statistically significant difference between groups （P 〉 0.05）.Conclusion methotrexate in combination with mifepristone in the treatment of ectopic pregnancy clinical curative effect is superior to methotrexate alone, is worthy of popularization and application.