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中老年男性人群代谢综合征和良性前列腺增生的相关性分析 被引量:2

Analysis of the Correlation Between Metabolic Syndrome and BPH in Middle and Old-aged Men
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摘要 目的 探讨中老年男性人群代谢综合征与良性前列腺增生(BPH)的相关性。方法 选择2008年5月至2013年7月于本院体检中心体检的中老年男性(≥50岁)共151例,检查一般项目包括年龄、身高、体质量、血压、既往史、国际前列腺症状评分表(IPSS)评分等。实验室检查包括空腹血糖、血脂、前列腺特异性抗原(PSA)等。影像学检查包括经直肠超声,并以此测量前列腺的体积;同时测量尿流率(Q M ax )。利用以上指标比较代谢综合征组和非代谢综合征组BPH患病率;同时比较代谢综合征组内各因素与BPH的相关性。结果 依据检查结果分为代谢综合征组(37例)和非代谢综合征组(114例)。代谢综合征组及非代谢综合征组BPH的发病率分别为32.4%(12/37)和12.3%(14/114)。两组之间相比IPSS、前列腺体积和血清PSA差异有统计学意义( P <0.05),QMax差异无统计学意义( P=0.071)。肥胖、高脂血症和糖尿病是BPH的危险因素(OR值分别为1.72、3.31和2.07,P值分别为0.042、0.029和0.046)。结论 代谢综合征检查者的BPH患病率较高,主要影响BPH患者的IPSS、前列腺体积和PSA。肥胖、高脂血症、糖尿病是BPH的危险因素。 Objective] To explore the correlation between metabolic syndrome and benign prostatic hyperplasia (BPH) in middle and old‐aged men .[Methods] Totally 151 middle and old‐aged men(≥50 years old) in physical exami‐nation center of our hospital from May 2008 to July 2013 were chosen .The general examinations included age ,height , weight ,blood pressure ,past history and IPSS score .The laboratory tests included fasting blood glucose ,blood lipids and PSA .The image test was transrectal ultrasound for measuring prostate volume .Urine flow rate(QMax) was measured . The incidence of BPH between metabolic syndrome and non‐metabolic syndrome was compared .The correlation of factors in metabolic syndrome with BPH was analyzed .[Results]According to examination results ,all cases were divided into metabolic syndrome group( n =37) and non‐metabolic syndrome group( n =114) .The incidence of BPH in metabolic syndrome group and non‐metabolic syndrome was 32 .4% (12/37) and 12 .3% (14/114) ,respectively .There was signifi‐cant difference in IPSS ,prostate volume and PSA between two groups( P〈0 .05) .There was no significant difference in QMax between two groups( P=0 .071) .Obesity ,hyperlipidemia and diabetes mellitus were the risk factors of BPH(OR=1 .72 ,3 .31 ,2 .07 ,P=0 .042 ,0 .029 ,0 .046) .[Conclusion]The morbidity of BPH in patients with metabolic syn‐drome is higher .IPSS ,prostate volume and PSA are the main influential factors of BPH patients .Obesity ,hyperlipi‐demia and diabetes are the risk factors of BPH .
作者 朱波 李勐
出处 《医学临床研究》 CAS 2014年第11期2140-2142,共3页 Journal of Clinical Research
关键词 代谢综合征X 前列腺增生 危险因素 Metabolic Syndrome X Prostatic Hyperplasia Risk Factors
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