传染性单核细胞增多症与多种病原体感染的关系

Relationship Between Infectious Mononucleosis and Various Pathogen Infection

目的 探讨儿童传染性单核细胞增多症（I M ）的临床特点与病原体感染多样性的关系。方法 对本院211例确诊为IM儿童进行回顾性分析，分别分为≤3岁组，3～6岁组，6～13岁组。结果 年龄≤3岁占63．9％，3～6岁占24．2％，6～13岁占11．9％；单种病原体感染96例占45．5％，混合病原体感染108例占51．2％，有7例占3．3％未找到病原体，混合感染患儿症状更多更重，经抗病毒及联合治疗，所有患儿好转出院。结论 IM中年龄≤3岁患儿多见，EB病毒是IM患儿最常见的病原体，多种病原体混合感染占多数，其病情更重，对混合感染患儿联合用药有效。

Objective]To explore the relationship between clinical features of infectious mononucleosis（IM ） in chil‐dren and the diversity of pathogen infection .[Methods]A total of 211 pediatric patients diagnosed as IM in our hospital were analyzed retrospectively and divided into less than 3 years old group ,3~6 years old group and 6~13 years old group .[Results] Pediatric patients with age ≤ 3 years old ,3~6 years old 6~13 years old accounted for 63 .9% , 24 .2% and 11 .9% ,respectively .The 96 patients with single pathogen infection accounted for 45 .5% ,and 108 patients with mixed pathogen infection accounted for 51 .2% ,and 7 patients with unknown pathogen accounted for 3 .3% .The symptoms of pediatric patients with mixed pathogen infection were more and even severe .After antiviral and combination therapy ,all pediatric patients were cured and discharged from hospital .[Conclusion] IM is commonly seen in children with age ≤ 3 years old .EB virus is the most common pathogen of IM in pediatric patients .The mixed pathogen infection is the majority and even severe .Combination therapy is effective for pediatric patients with mixed infection .