洗胃后配合间歇胃肠减压治疗新生儿顽固性呕吐的疗效及安全性分析

The Effect and Safety of Intermittent Gastrointestinal Decompression Therapy after Gastric Lavage in the Treatment of Neonatal Intractable Vomiting

目的:探讨洗胃后配合间歇胃肠减压对新生儿顽固性呕吐的治疗效果和安全性。方法:选取2008年9月-2012年12月本院确诊治疗的顽固性呕吐新生患儿136例,依据随机分配原则分为减压组和对照组各68例,对照组患儿给予常规综合治疗和温盐水洗胃治疗,减压组在此基础上给予间歇胃肠减压治疗,对比分析两组患儿的临床治疗效果、胃肠功能恢复和复发情况。结果:减压组患儿呕吐次数、胃肠功能恢复时间均明显低于对照组,体重恢复程度明显高于对照组,差异有统计学意义(P<0.05);减压组患儿总有效率明显高于对照组,差异有统计学意义(P<0.05);减压组患儿呕吐复发率低于对照组,差异有统计学意义(P<0.05);两组患儿均未出现慢性肠炎、坏死性肠炎等严重胃肠不良反应。结论:洗胃后配合间歇胃肠减压治疗可有效缓解新生儿顽固性呕吐症状,加快胃肠功能恢复,有助于新生患儿体重的恢复,降低呕吐复发的发生,且具有较高的安全性,值得临床进一步推广。

Objective：To discuss the effect and safety of intermittent gastrointestinal decompression therapy after gastric lavage in the treatment of neonatal intractable vomiting.Method：136 newborn child with intractable vomiting were selected from September 2008 to December 2012 in our hospital.According to the random distribution, all newborn child were divided into relief group（68 cases） and control group（68 cases）, control group received routine comprehensive treatment and warm saline lavage treatment;observation group received the intermittent gastrointestinal decompression therapy on this basis;clinical therapeutic effects, gastrointestinal function recovery and recurrence of two groups were analyzed.Result：Vomiting frequency, gastrointestinal function recovery time of relief group were significantly lower than those of the control group.Weight recovery of relief group was significantly higher than that of the control group, the difference was statistically significant（P〈0.05）.Relief group vomiting recurrence rate of relief group was lower than that of the control group（P〈0.05）.Two groups were not in chronic enteritis, severe necrotizing enteritis（P〈0.05）.Conclusion：Intermittent gastrointestinal decompression treatment after gastric lavage can effectively alleviate the newborn intractable vomiting, accelerate gastrointestinal functional recovery, it＇s good for newborn child with the recovery of body weight, reduce the occurrence of recurrent vomiting and has the high security, it＇s worth for further clinical promotion.