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右美托咪定用于电生理监测下颞叶癫痫病灶切除手术的临床观察 被引量:4

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摘要 癫痫严重影响患者的工作生活及整体健康情况,30%~40%的患者对于药物治疗的反应不佳[1]。目前癫痫灶切除术已被药物难治性癫痫患者广泛接受。手术中麻醉要求能通过皮层脑电图(Electrocorticography,EcoG)定位致痫灶,避免麻醉药物干扰癫痫波的监测,同时保持良好的镇静镇痛。右美托咪定的主要作用靶点是脑干蓝斑的α2肾上腺素能受体(α2-AdRs)[2]。独特的清醒镇静特性成为右美托咪定用于功能神经外科手术麻醉用药的考虑之一。本文在颞叶癫痫病灶切除手术中应用右美托咪定,观察其在全麻时对电生理监测的影响。
出处 《临床麻醉学杂志》 CAS CSCD 北大核心 2014年第12期1237-1238,共2页 Journal of Clinical Anesthesiology
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参考文献8

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共引文献8

同被引文献52

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