52例头孢曲松钠不良反应分析

Analysis of 52 cases adverse reaction of ceftriaxone sodium

目的 :探讨头孢曲松钠不良反应发生的特点及相关因素,为临床合理用药提供参考。方法 :采用回顾性研究方法,对上海交通大学附属第一人民医院2006年1月-2012年12月上报的因使用头孢曲松钠出现的52例不良反应报告进行统计和分析。结果 :头孢曲松钠所致不良反应主要为皮肤及附件损害(33例,63.5%)和过敏性休克(5例,9.6%)。结论 :应加强对头孢曲松钠不良反应的监测,注意其过敏性休克等严重不良反应,保障用药安全。

Objective：To explore the characteristics and the correlation factors of adverse reaction resulting from ceftriaxone sodium so as to provide a reference for the clinically reasonable medication.Methods：Fifty two cases of adverse reaction of ceftriaxone sodium collected by our hospital from January, 2006 to December, 2012 were statistically analyzed through retrospective research.Results： The adverse reactions include mainly 33 cases （63.5%） skin and appendix harm, 5 cases （9.6%） anaphylactic shock.Conclusion： It was very necessary to strengthen the monitoring of the adverse reaction and pay attention to allergic shock to promote the reasonable application of this drug.