布地奈德与特布他林雾化治疗慢性阻塞性肺疾病的临床评价

Clinical Evaluation of Atomization on the Treatment of Chronic Obstructive Pulmonary Disease with Budesonide and Terbutaline

目的：评价分析布地奈德与特布他林雾化治疗慢性阻塞性肺疾病的临床疗效。方法按照数字表法将2012年6月～2014年6月我院收治的146例慢性阻塞性肺疾病患者随机的分成对照组和观察组各73例，对照组患者采取常规治疗方法，观察组在常规治疗基础上采取布地奈德与特布他林雾化治疗，对两组患者治疗后的总有效率和肺功能指标FEV 1改善情况进行比较。结果对照组患者治疗后的总有效率为79.5%，观察组患者治疗后的总有效率为95.9%，两组比较差异具有显著统计学意义（P＜0.01）；治疗后，观察组患者FEV1高于对照组患者，两组比较差异具有统计学意义（P＜0.05）。结论慢性阻塞性肺疾病应用布地奈德与特布他林雾化治疗能够有效的缓解气道痉挛、减轻气道炎症反应，促进肺功能的显著改善，有助于患者的康复，是一种安全有效的治疗手段。

Objective To evaluate and analysis clinic effect of atomization on the treatment of chronic obstructive pulmonary disease with budesonide and terbutaline. Methods 146 cases patients with COPD from June 2012 to June 2014 in our hospital were randomly divided into control group（apply the routine treatment methods） and observation group（apply atomization of budesonide and terbutaline） by the digital meter method,each group has 73 cases,to compared the total ef ective rate and the improvement of FEV1. Results The total ef ective rate of control group was 79.5%, The total ef ective rate of observation group was 95.9%,the dif erence was significant（P〈0.01）;After treatment, the FEV1 of observation group was higher than that of control group the dif erence was significant（P〈0.05）. Conclusion Application of atomization on the treatment of COPD could ef ectively relieve the airway, reduce airway inflammation, improve lung function significantly,.It was helpful for the recovery of patients,It was a safe and ef ective treatment .It was worthy of clinical popularization and application.