研究阿立哌唑与奋乃静联合治疗酒精中毒性精神障碍的临床效果

Clinical Study on the Effect of Aripiprazole and Perphenazine Combined Treatment of Alcoholism Mental Disorder

目的研究探讨阿立哌唑与奋乃静联合应用治疗酒精中毒性精神障碍的临床效果。方法选取我院2010年9月~2013年5月间就诊的酒精中毒性精神障碍患者60例,随机分为观察组和对照组。对照组单用奋乃静片进行治疗,观察组在对照组的基础上联用阿立哌唑片进行治疗。结果观察组总有效率为93.3%,对照组总有效率为73.3%,两组相比,差异显著;治疗一段时间后,观察组患者不良反应的发生率为20.0%,对照组患者不良反应的发生率为46.7%,两组相比差异显著。结论采用阿立哌唑与奋乃静联合使用对酒精中毒性精神障碍进行治疗,不良反应少,临床疗效较好。

Objective To explore clinical curative effect of aripiprazole and perphenazine combination in the treatment of alcoholism mental disorder. Methods 60 cases of patients with mental disorders were selected in our hospital in 2010 September^2013 May between the treatment of alcoholism, were randomly divided into observation group and control group. The control treatment group with single Perphenazine Tablets, on the basis of the observation group in the control group were treated with AripiprazoleTablets. Results the total effective rate of observation group was 93.3%, the control group the total effective rate was 73.3%, compared to the two groups, significant difference;after a period of treatment, patients in the observation group the incidence rate of adverse reactions of 20%patients in the control group, the incidence rate of adverse reactions was 46.7%, difference between the two groups was significant. Conclusion the use of aripiprazole and perphenazine combined use of treatment for alcoholic psychosis, less adverse reaction, good clinical curative effect.