不同药物治疗口腔念珠菌病的对比研究

The Comparative Analysis of Different Medical Approaches in Treatment of Oral Candidiasis

目的：研究不同药物对口腔念珠菌病的治疗效果。方法搜集2013年7月～2014年7月我院接收的口腔念珠菌病96例患者，按照不同治疗药物分为甲组、乙组、丙组各32例。给予甲组酮康唑治疗，给予乙组制霉菌素治疗，给予丙组氟康唑治疗。观察甲组、乙组、丙组的治疗效果，并比较。结果与甲组相比，乙组和丙组治疗有效率较高，不良反应较少，有明显差异，有统计学意义（P＜0.05）。结论氟康唑、制霉菌素对口腔念珠菌病的临床疗效优于酮康唑，且不良反应较少。

Objective The treatment efficacy of different medical approaches in treatment of oral candidiasis is to be investigated. Methods Choose 96 patients of oral candidiasis who are treated in hospital from July 2013 to July 2014 and separate them into group A, group B and group C according to different medical treatment approaches. Patients in group A are given Ketoconazole treatment, and patients in group B are given Nystatin treatment, while patients in group C are given fluconazole treatment, and then observe and compare treatment efficacy of these three groups. Results Compared to group A, both group B and group C have higher efficiency rate and less side effects, there is a clinical efficacy differential between these three groups and such a differential has statistic value（P〈0.05）. Conclusion Fluconazole and Nystatin treatment is much more effective to cure oral candidiasis than Ketoconazole treatment with few less side effects. Thus, such a treatment approach is quite worthwhile to be clinical y promoted and applied.