摘要
对叔丁基杯[4]芳烃与对甲苯磺酸酯基乙氧基对苯甲醛反应生成对叔丁基杯[4]芳烃-1,3-二醛基衍生物1,对叔丁基杯[4]芳烃-1,3-二醛基衍生物1与金刚烷甲酰肼进行分子间缩合反应得到含杯[4]芳烃的金刚烷甲酰腙化合物2,并利用1H NMR,13C NMR,MS和元素分析对目标化合物的结构进行了表征。初步的抗菌试验表明,该化合物表现出较好的抗菌活性。
p-Ten-butylcalix[4]arene reacted with p-toluene sulfonic acid esteryl ethoxy-p-benzaldehyde to give 1,3-bis[2-(p-formylphenoxy)ethyloxy]-p-tertbutylcalix[4]arene 1. Reacting 1,3-bis[2-(p-formylphenoxy)ethyloxy]-p-tert-butylcalix[4]arene I with adamantane carboxylic acid hydrazide by intermolecular condensation, a novel adamantane carboxylic acid hydrazone derivative containing calix[4]arene 2 was prepared in high yield. The structure of new compound was characterized by elemental analyses, 1H NMR, 13C NMR and ESI-MS spectra.
出处
《广东化工》
CAS
2015年第2期61-62,共2页
Guangdong Chemical Industry
关键词
金刚烷甲酰腙
杯[4]芳烃
合成
抑菌活性
adamantane carboxylic acid hydrazone
biscalix[4]arene
synthesis
antibacterial activity