乙烯基碳上的亲核取代反应

Nucleophilic Substitution Reactions at Vinylic Carbons

综述了近二十年来关于sp2杂化碳,主要是乙烯基碳上发生的亲核取代反应的研究进展.讨论了乙烯基碳上的亲核取代反应的理论支持,阐明了其在有机合成中,特别是在杂环化合物的合成中的重要应用.同时还总结了其他不饱和原子如sp2杂化氮的亲核取代反应的研究以及应用.

The recently research progress in the nucleophilic substitution reactions at the sp2-carbons, mainly at the vinylic carbons is reviewed. The theoretical studies on the nucleophilic substitution reactions at the vinylic carbons, and their applica-tions in organic synthesis, especially in the synthesis of heterocycle compounds, are illustrated. And, researches and applica-tions of the nucleophilic substitution reactions at other unsaturated atoms like sp2 nitrogens are also discussed.