新生儿胆红素与蛋白定量检测的临床意义研究

The Clinical Analysis of Quantitive Detection of Neonatal Bilirubin and Protein

目的：探讨新生儿不同组总胆红素浓度（TBIL）中总蛋白（TP）、白蛋白定量（ALB）、前白蛋白（PA）含量变化,为临床对新生儿黄疸治疗提供实验数据。方法：根据TBIL浓度不同分为低〈34.00μmol/L、中34.0~220.99μmol/L,高≥221.00μmol/L,统计分析三组TP、ALB、PA含量的差异。结果：TP、ALB、PA低组结果分别为（44.11±6.44）g/L、（30.32±3.96）g/L、（45.80±22.87）mg/L,中组结果分别为（48.78±6.02）g/L、（33.99±3.93）g/L、（62.97±24.15）mg/L、高组结果分别为（54.07±4.40）g/L、（36.66±2.74）g/L、（66.70±19.24）mg/L。采用独立样本的t检验,三组比较差异有统计学意义（P〈0.05）。结论：对出生后新生儿进行TBIL、TP、ALB、PA检测对新生儿黄疸的治疗评估具有一定临床指导意义。

Objective： To investigate the changes of TP, ALB, PA of in different of TBIL concentration and provide experimental data for clinical treatment of neonatal jaundice. Method： The TBIL were divided into three groups： low34.00 μmol/L, middle 34.0-220.99 μmol/L, high ≥ 221.00 μmol/L, and the TP, ALB, PA was analyzed in different TBIL levels. Result： The low group TP, ALB, PA result was（44.11±6.44）g/L,（30.32±3.96）g/L,（45.80±22.87）mg/L. The middle was（48.78±6.02）g/L,（33.99±3.93）g/L,（62.97±24.15）mg/L. And the high（54.07±4.40）g/L,（36.66±2.74）g/L,（66.70±19.24）mg/L, there was a significant difference between the three groups（P〈0.05）. Conclusion： It is a certain clinical significance for assessment of neonatal jaundice to detection of neonatal TBIL, TP, ALB, PA.