摘要
恶性肿瘤患者围术期存在免疫功能抑制,且术后疼痛可抑制机体免疫功能.有效的术后镇痛能缓解围术期机体免疫功能抑制,并减少肿瘤复发转移.然而,不同镇痛药物及镇痛方式对机体免疫功能的影响不尽相同.本文就不同镇痛药物及镇痛方式对恶性肿瘤患者围术期免疫功能影响的研究进展作一综述,以期为肿瘤患者提供更合适的术后镇痛方案,有利于术后免疫平衡调节,减少肿瘤复发风险并改善预后.
Perioperative immunosuppression exists in cancer patients are as a result of their own disease,and postoperative pain inhibit immunological function.The effective postoperative analgesia can relieve the suppression of cell-mediated immunity,as well as reducing tumor recurrence and metastasis.However,diverse range of analgesic agents and techniques have a different impact on immune function.This article reviews the influence of various analgesic agents and techniques on the perioperative immune function of cancer patients so as to provide more suitable analgesia techniques,which is beneficial for regulating of immune balance,lessening tumor recurrence and improving prognosis.
出处
《国际外科学杂志》
2014年第12期845-849,共5页
International Journal of Surgery
基金
基金项目：国家自然科学基金面上项目（No.81172364）
安徽省科技攻关资助项目（No.1301042199）
安徽省卫生厅医学科研重点基金资助项目（No.2010A006）
关键词
镇痛
免疫
肿瘤
围术期
Analgesia
Immunity
Neoplasms
Perioperative period
