烟雾病非儿童患者脑微出血特点研究

The research of cerebral hemorrhage characteristics in grown patients with moyamoya disease

目的对烟雾病非儿童患者脑微出血的发生情况、分布方式以及影响因素进行观察和分析。方法选取80例烟雾病非儿童患者为研究对象,经进一步影像学检查后根据其脑微出血情况分为脑微出血阳性组和脑微出血阴性组,比较2组出血数量、分布情况以及其他临床资料。结果脑微出血分布区域以深部结构区较为集中24处,其次为幕下区6处和脑叶区5处,分布差异有统计学意义(χ2=86.070,P=0.000)。脑微出血阳性组收缩压和空腹血糖水平较脑微出血阴性组明显升高,差异有统计学意义(P<0.05)。其中空腹血糖水平升高是出现脑微出血的独立危险因素(P<0.05)。结论烟雾病非儿童患者脑微出血主要出现于深部结构区侧脑室旁白质,而空腹血糖水平升高可能是其脑微出血发生的独立危险因素。

Objective To investigate and analyze the cerebral hemorrhage characteristics in grown patients with moyamoya disease.Methods 80 grown patients with moyamoya disease were divided into positive cerebral microbleed group and negative cerebral microbleed group according to cerebral microbleed.The hemorrhage quantity and distribution and clinical data of two groups were compared.Results Cerebral microbleed distribution areas from more to less in turn were deep structure area（68.57%）,under curtain area（17.14%）and leaf area（14.29%）,which had significant difference（χ^2= 86.070,P =86.070）.The systolic blood pressure and fasting blood glucose of positive cerebral microbleed group were higher than these of negative cerebral microbleed groups,which had significant difference（P〈0.05）.Elevated fasting glucose level was an independent risk factor for the development of cerebral microbleed（P〈0.05）.Conclusion Cerebral microbleed area in grown patients with moyamoya disease is mainly in the deep structure area and lateral ventricle narrator,and the elevated fasting glucose level may be independent risk factor for the developments of the cerebral micro-bleed occur.