关节液各检验指标与关节炎类型的相关性

Correlation between each test indicator of synovial fluid and arthritis types

目的找到关节液中各检验指标的改变与不同病因之间的相关性。方法将关节炎病例按常见类型分为6组,即骨性关节炎、反应性关节炎、痛风性关节炎、类风湿关节炎、创伤性关节炎、其他类型关节炎。每组随机选择37例患者,抽取关节液,并检测关节液中白细胞(WBC)、总蛋白(TP)、清蛋白(ALB)、糖(GLU)、尿酸(UA)、抗链球菌溶血素O(ASO)、类风湿因子(RF)、C反应蛋白(CRP)、免疫球蛋白G(IgG)、免疫球蛋白A(IgA)、免疫球蛋白M(IgM)、补体C3、补体C4、白细胞介素(IL)-1β、IL-6、肿瘤坏死因子-α(TNF-α)的水平,将检测数据进行分组统计。结果除CRP、IgG、IgA外,其余各测定指标(WBC、TP、ALB、GLU、UA、ASO、RF、IgM、C3、C4、IL-1β、IL-6、TNF-α)均存在差异。结论关节液中诸多成分的水平与病因相关。

Objective To find the correlation between each test indicator change of synovial fluid with different etiologies .Methods The cases of arthritis were divided into 6 groups according to the common types ：osteoarthritis , reactive arthritis ,gouty arthritis ,rheumatoid arthritis ,traumatic arthritis and other types of arthritis .37 cases were randomly extracted from each group and the synovial fluid was extracted for detecting the white blood cells （WBC） count ,total protein（TP） ,albumin（ALB） ,glucose（GLU） ,uric acid（UA） ,anti‐streptolysin O（ASO） ,rheumatoid fac‐tor（RF）,C‐reactive protein（CRP）,immunoglobulin G（IgG）,immunoglobulin A（IgA）,immunoglobulin M（IgM）, complement C3 ,complement C4 ,interleukins IL‐1β（IL‐‐1β） ,IL‐6 and tumor necrosis factor‐a（TNF‐a） levels .The de‐tected data were performed the statistics by grouping .Results Except CRP ,IgG ,and IgA ,other detected indicators had differences ,including WBC ,TP ,ALB ,GLU ,UA ,ASO ,RF ,IgM ,C3 ,C4 ,IL‐1β,IL‐6 and TNF‐a .Conclusion The contents of many components in synovial fluid are correlated with etiology .