XN-1000希森美康对孕妇外周静脉血分析提示与细胞涂片染色分析的相关性

Correlation between analysis prompts in XN-1000 Sysmex hematology analyzer and blood cell smear staining analysis for peripheral venous blood in pregnant women

目的探讨XN-1000希森美康细胞分析仪对孕妇外周静脉血白细胞分类计数、有核红细胞计数分析提示与相关细胞涂片染色人工分析结果相关性及意义。方法采用XN-1000型希森美康细胞分析仪对妇产科采集的280份外周静脉血进行白细胞分类计数、有核红细胞计数分析,同时对应外周静脉血标本进行细胞涂片染色分析,比较仪器分析和细胞染色人工分析结果。结果仪器分析重复性良好,仪器分析和细胞染色人工分析具有较高的相关性,报警提示结果和细胞染色人工分析阳性结果特异性大于95%,灵敏度100%,阳性预测值大于90%,阴性预测值100.00%。结论 XN-1000希森美康细胞分析仪分析报警提示可以有效筛选阳性标本,同时对阳性标本需要细胞染色人工分析,避免假阳性结果。

Objective To investigate the correlation between the analysis prompts of white blood cells （WBC） count and nucleated red blood cells （NRBC） count by the XN‐1000 Sysmex hematology analyzer and the related blood cell smear staining artificial analysis for peripheral venous blood in pregnant women .Methods 280 specimens of pe‐riphery venous blood from pregnant women in our hospital were collected and simultaneously detected the WBC count and NRBC count by using the XN‐1000 Sysmex hematology analyzer and the blood cell smear staining analysis .Then the detection results were compared between the two kinds of detection method .Results The instrumental analysis had good reproducibility .The higher correlation existed between the instrumental analysis and blood cell staining arti‐ficial analysis .The specificity of alarm suggesting analysis results and the positive results of the cell staining artificial analysis was greater than 95% ,the sensitivity was 100% ,the positive prediction value was greater than 90% and the negative prediction value was 100 .00% .Conclusion The analysis alarm prompts of the XN‐1000 Sysmex hematology analyzer can effectively screen the positive samples ,at the same time the positive samples need to conduct the cell staining artificial analysis for avoiding the false positive results .