氧驱动雾化吸入补钾对呼吸系统安全性的影响

Research on the safety of repairing a potassium through oxygen driven atomizing inhalation

目的:观察氧驱动雾化吸入补钾对人体呼吸系统安全性的影响。方法:将60例中度低钾血症患者入院后随机等分为观察组和对照组,两组患者均未予其他补钾方法治疗,对照组给予10%氯化钾注射液加入5%葡萄糖或生理盐水静脉滴注;观察组给予10%氯化钾注射液进行氧驱动雾化吸入补钾治疗。结果:两组患者补钾治疗前与自身补钾后各时点段的呼吸频率、血氧饱和度及补钾效果比较,均无统计学意义(P>0.05);两组患者补钾后即时Pa CO2,Pa O2比较,观察组Pa CO2在正常范围内低于对照组,Pa O2高于对照组,差异有统计学意义。结论:氧驱动雾化吸入补钾是安全的,不会影响呼吸系统的生理功能,而且在补钾的过程中患者可得到氧气供给,值得临床推广。

Objective：Observation on the safety for respiratory system by application of repairing a potassium through oxygen driven atomizing inhalation. Methods：60 cases of moderate hypokalemia patients were randomly divided into two groups：observation group and control group with 30 cases in each group, etiological treatment and routine nursing were adopted in both groups,after proper amount of repairing a potassium was calculated,control group used intrave-nous drop infusion of 10% of potassium chloride injection with 5% glucose,while observation group used repairing a potassium throgh oxygen driven atomi-zing inhalation of 10% potassium chloride injection. No other methods of repairing a potassium were adopted in both groups. Results：It showed no statistical significance at different period of time before and after repairing a potassium on respiratory rate oxyhemoglobin saturation and effect of repairing a potassium in both groups （P〈0. 05）. It showed a difference on PaCO2 and PaO2 and statistical significance. After repairing a potassium in both groups,observation group′s PaO2 was lower and PaO2 was higher than that in control group within the normal range. Conclusion：Repairing a potassium through oxygen driven at-omizing inhalation is safe,non side effect on physiological function of respiratory system,oxygen supplementation is also provided at the same time during re-pairing a potassium,it deserves clinical expansion.