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EZH2的功能及在肿瘤中的表达 被引量：7

Expression of EZH2 and the function in tumor
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摘要 EZH2在多种肿瘤中呈高表达,其过表达与组织学分化程度、临床分期、肿瘤大小、淋巴结转移和预后相关。本文就EZH2的结构、功能、与沉默机制相关的其他酶之间的联系,及其在肿瘤中的表达作一综述。 Overexpression of the enhancer of zeste homolog 2 （EZH2） protein has been found in broad range of cancer types.Its overexpression related with the histological differentiation degree,clinical stage,tumor size,lymph node metastasis and prognosis. This paper reviewed the relationship between the structure,function of EZH2 with the silencing mechanism of other enzyme,and the expression of EZH2 in tumors.
作者 杨青梅 白松 雷又鸣 施云飞 王智华
机构地区 昆明医科大学 昆明医科大学第一附属医院
出处 《中国老年保健医学》 2014年第6期72-75,共4页 Chinese Journal of Geriatric Care
关键词 EZH2 肿瘤 miRNA-101 表观遗传 EZH2, tumour,miRNA-101 ,epigenetics
分类号 R730.2 [医药卫生—肿瘤]
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二级参考文献29

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共引文献12

同被引文献79

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引证文献7

二级引证文献12

中国老年保健医学
2014年 第6期

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