期刊文献+

HGF在脑胶质瘤的表达及临床意义 被引量:1

Expression and Clinical Significance of Genes HGF in Gliomas
下载PDF
导出
摘要 目的探讨肝细胞生长因子(HGF)在人脑胶质瘤中的表达水平以及预后。方法免疫组化染色后,检测49例HGF蛋白表达情况。分析脑胶质瘤的恶性程度、发病年龄、性别之间的相关性。结果 HGF随病理分级的增加,其表达水平呈显著性差异(P<0.05)。HGF与脑胶质瘤发病年龄、性别之间阳性表达水平无明显差异(P>0.05)。结论 HGF在脑胶质瘤中的表达与脑胶质瘤恶性级别程度有显著相关。HGF在脑胶质瘤中表达与患者性别、年龄无关。
出处 《河南科技大学学报(医学版)》 2014年第4期243-244,共2页 Journal of Henan University of Science & Technology:Medical Science
  • 相关文献

参考文献6

  • 1Ndratschke N,Crosu AL,Molls M,et a1.Propectives in the treatment of malignant gliomas in adults[J].Anticancar Res,2001,21(5):3541-3543.
  • 2Wata Ilabe Y,Nakai H,Ueda H,et a1.Platelet-derived endothelial cell growth factor predicts of proession and recurrence in primary eithelial ovarian cancer[J].Cancer Lett,2003,200(2):173-176.
  • 3Yano H,Hara A,Murase S,et a1.Expression of hepatocyte growth factor and matrix metalloproteinase-2 in human glioma[J].Brain Tumor Pathol,2001,18(1):7-13.
  • 4Webb CP,Hose CD,Koochekpour S,et al.The geldanamycins are potent inhibitors of the hepatocyte growth factor/scatter factor-met-urekinase plasminogen activator plasmin pmteolytic network[J].Cancer Res,2000,60(2):342-349,.
  • 5李纲,张元芳,丁强,严春寅,温端改.浅表性膀胱癌PD-ECGF mRNA表达的意义[J].中华外科杂志,2004,42(8):478-481. 被引量:4
  • 6Naim R,Chang RC,Sadick H,et a1.Influence of hepatocyte growth factor scatter factor on fibroblast growth facter levels in external auditory canal cholesteatoma cell culture[J].In Vi Vo,2005,19(3):599-603.

二级参考文献19

  • 1刘耀庭,程伟,李秀霞.泌尿外科肿瘤发病情况的变化[J].临床泌尿外科杂志,1997,12(1):47-48. 被引量:39
  • 2顾方六.尿路上皮肿瘤临床[A].见:吴阶平.泌尿外科[C].济南:山东科学技术出版社,1993.456.
  • 3Soloway MS,Sofer M,Vaidya A.Contemporary management of stage T1 transitional cell carcinoma of the bladder.J Urol,2002,167:1573-1583.
  • 4Moghaddam A,Zhang HT,Fan TP,et al.Thymidine phosphorylase is angiogenic and promotes tumor growth.Proc Natl Acad Sci U S A,1995,92:998-1002.
  • 5Komuro H,Kaneko S,Kaneko M,et al.Expression of angiogenic factors and tumor progression in human neuroblastoma.J Cancer Res Clin Oncol,2001,127:739-743.
  • 6Ueda M,Terai Y,Kumagai K,et al.Correlation between thymidine phosphorylase expression and invasion phenotype in cervical carcinoma cells.Int J Cancer,2001,91:778-782.
  • 7Shimaoka S,Matsushita S,Nitanda T,et al.The role of thymidine phosphorylase expression in the invasiveness of gastric carcino-ma.Cancer,2000,88:2220-2227.
  • 8Kawakami S,Kageyama Y,Fujii Y,et al. Inhibitory effect of N-acetylcysteine on invasion and MMP-9 production of T24 human bladder cancer cells.Anticancer Res,2001,21: 213-219.
  • 9Ishikawa F,Miyazono K,Hellman U,et al.Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor.Nature,1989,338:557-562.
  • 10Moghaddam A,Bicknell R.Expression of platelet-derived endothelial cell growth factor in Escherichia coli and confirmation of its thymidine phosphorylase activity.Biochemistry,1992,31:12141-12146.

共引文献3

同被引文献12

引证文献1

二级引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部