1Sandrine Turpault, William Brian, Robert Van Horn, et al. Pharmacokinetic assessment of a five-probe cocktail for CYPs 1A2, 2C9, 2C19, 2D6 and 3A[J].British Journal of Clinical Phar- macology, 2009,68(6) : 928-935.
2Ophelia Q. P. Yin, Sherry S. L. Laml, Cindy M. Y. Lol, Moses S. S. Chowl.Rapid determination of five probe drugs and their metabolites in human plasma and urine by liquid chromatog- raphy/tandem mass spectrometry: application to cytochrome P45o phenotyping studies [J].Rapid Commun. Mass Spectrom,2004,18: 2921-2933_.
3Diana M. Feidt, Kathrin Klein, Ute Hofmann, et al. Profiling Induction of Cytoehrome P450 Enzyme Activity by Statins Using a New Liquid Chromatography-Tandem Mass Spectrometry Cocktail Assay in Human Hepatoeytes[J].Drug Metabolism and Disposition, 2010,38(9) : 1589-1597.
5Mallorie Clement Jerdi, Youssef Daali, Mitsuko Kondo Oestre- icher, et al. A simplified analytical method for a phenotyping cocktail of major CYP4s0 biotransformation routes [J].Joumal of Pharmaceutical and Biomedical Analysis, 2004,35:1203-1212.
6Susan P. Rhodes , Jennifer N. Otten, Gary P. Hingorani, et al. Simultaneous assessment of cytochrome P450 activity in cultured human hepatocytes for compound-mediated induction of CYP3A4, CYP2B6, and CYP1A2[J].Journal of Pharmacological and Toxico- logical Methods, 2010.
8Hye Young Ji , Sung Yeon Kim , Dong Kyun Kim, et al. Ef- fects of Eupatilin and Jaceosidin on Cytochrome P450 Enzyme Activ- ities in Human Liver Microsomes [J].Molecules, 2010,15 : 6466- 6475.
9Sang Kyu Leel, Yoon Kiml, Changbae Jin, et al. Inhibitory effects of deoxypodophyllotoxin from Anthriscus sylvestris on hu- man CYP2C9 and CYP3A4 [J]. Planta Med,2010,76:701-704.
二级参考文献14
1Meyer U A. Overview of enzymes of drug metabolism. J Pharmacokinet Biopharm, 1996,24(5):449～459
2Steven A W, Mark V B, Barbara J R. The human drug metabolizing cytochromes P450. J Pharmacokinet Biopharm, 1996,24(5):461～473
3Adedoyin A, Frey R F, Mauro K, et al. Chlorquine modulation of specific metabolizing enzymes activities: investigation with selective five drug cocktail. Br J Clin Pharmacol, 1998,46:215～219
4Frey R F, Adedoyin A, Porter J A, et al. Validation of the five-drug "Pittsburgh cocktail" approach for assessment of selective regulation of drug metabolizing enzymes. Clin Pharmacol Ther, 1997,62:365～376
5Lowry O H, Rosebrogh N J, Farr A L. Protein measurements with the folin phenol reagent. J Biol Chem, 1951,193:265～273
6Omera T, Sato R. The carbon monoxide-binding pigment of liver microsomes. J Biol Chem, 1964,239(7):183～189
7Shalini V K, Srinivas L. Lipid peroxide induced DNA damage: protection by turmeric. Molecular Cellular Biochem, 1987,77(1):3～10
8Srinivas L, Shalini V K, Shylaja M. Turmerin: A water soluble antioxidant peptide from turmeric. Arch Biochem Biophys, 1992,292(2):617～623
