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47例老年晚期乳腺癌内分泌治疗的临床分析 被引量:2

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摘要 目的探讨他莫昔芬和来曲唑对老年晚期乳腺癌患者的临床疗效及预后是否有差异。方法回顾性分析47例老年晚期乳腺癌患者临床资料,按照接受他莫昔芬(20例)和接受来曲唑(27例)治疗分为2组,比较2组疗效及预后关系。结果 47例患者中他莫昔芬组获CR 2例,PR 3例,SD9例,PD 6例,有效率为25%;来曲唑组获CR 3例,PR 7例,SD 8例,PD 9例,有效率为37%,2组有效率差异无统计学意义(P=0.529)。他莫昔芬组和来曲唑组的中位无瘤生存时间DFS分别为13个月和15个月(P=0.599),中位总生存期OS分别为23.5个月和28个月(P=0.337)。结论他莫昔芬和来曲唑在老年晚期乳腺癌患者内分泌治疗疗效及预后无明显差异。
出处 《当代医学》 2014年第36期129-130,共2页 Contemporary Medicine
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