摘要
目的探讨缺血修饰白蛋白(IMA)、肌钙蛋白(cTnI)、肌红蛋白(MYO)、肌酸激酶同工酶(CK-MB)检测在急性冠状动脉综合征的早期发现中的应用价值。方法选择100例急性冠状动脉综合征(ACS)患者,在胸痛发作后3小时内检测缺血修饰白蛋白(IMA)、肌钙蛋白(cTnI)、肌红蛋白(MYO),肌酸激酶同工酶(CK-MB),同时选择100例健康查体者为对照组,做相同检测,观察各种心肌标志物的变化。结果 ACS组与对照组的检测结果进行对比,4项指标的差异均具有统计学意义(P<0.05)。ROC下曲线面积显示,IMA仅次于cTnI,高于MYO和CK-MB。结论 IMA、MYO、cTnI、CK-MB联合检测在急性冠脉综合征(ACS)早期诊断中具有重要的临床意义。
Objective To explore the clinical value of Ischemia modified albumin (IMA), Cardiac troponin I (cTnI) ,Myohemoglobin (MYO) and Creatine kinasc isozymes (CK-MB) detection in the early diagnosis of acute coronary syndrome(ACS). Methods The serum levels of IMA, cTnI, MYO and CK-MB in 100 patients with acute coronary syndrome (ACS) at 3 hours after chest pain and in 100 healthy cases were detected. Results There were significantly difference on the IMA, cTnI, MYO and CK-MB between ACS group and control group (P 〈 0.05 ). The areas under ROC curve in ACS group was lower than cTnI, but higher than MYO and CK-MB. Conclusion The combined detection of IMA, cTnI, MYO and CK-MB in acute coronary syndrome have a significant clinical value in the early diagnosis of ACS.
出处
《标记免疫分析与临床》
CAS
2014年第6期671-673,共3页
Labeled Immunoassays and Clinical Medicine
基金
国家高技术研究发展计划(863计划)课题资助
课题编号:2011AA02A111