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核苷(酸)类似物联合TACE治疗中晚期原发性肝癌的效果 被引量:3

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摘要 原发性肝癌是指来源于肝脏上皮细胞的恶性肝瘤,其中肝细胞癌最常见,约占80%-90%,且多伴有慢性肝炎病毒感染,与乙型肝炎、肝炎后肝硬化关系最密切,由于起病隐匿,患者就诊时大多已属于中、晚期。根据国际抗癌协会的TNM分期为1r3或T4期。临床手术切除率较低,且大多数患者常因为肝脏储备功能差,影响经皮肝动脉栓塞化疗术(TACE)的效果。因此,经核苷(酸)类似物抗病毒治疗,能有效抑制乙肝病毒复制,从而改善肝脏功能,达到Child—PughA或B级,为TACE创造良好条件,从而明显延长肝癌患者生存时间,提高了患者生活质量。
出处 《实用临床医药杂志》 CAS 2014年第21期187-189,共3页 Journal of Clinical Medicine in Practice
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