垂体后叶素联合酚妥拉明治疗支气管扩张合并咯血患者的临床疗效分析

Analysis of Clinical Efficacy of Pituitrin and Phentolamine in Treatment of Patients with Bronchiectasis with Hemoptysis

目的探讨采用垂体后叶素联合酚妥拉明治疗支气管扩张合并咯血患者的临床疗效。方法按照数字随机表法将我院近年来收治的86例支气管扩张合并咯血患者平均分为观察和对照2组,所有患者均给予镇咳、化痰、抗感染、对症支持等常规治疗,观察组患者在此基础上应用垂体后叶素联合酚妥拉明治疗,比较两组患者的治疗总有效率。结果观察组患者治疗总有效率为95.3%,显著高于对照组患者的76.7%,组间差异可见统计学意义(P<0.05)。观察组患者用药过程中2例出现腹痛,2例出现胸闷,患者均能耐受,未影响治疗。结论垂体后叶素与酚妥拉明联合应用是一种治疗支气管扩张合并咯血患者的理想方法,应在临床大力推广使用。

Objective To investigate the clinical effect of pituitrin combined with phentolamine in the treatment of patients with bronchiectasis with hemoptysis. Methods In our hospital in recent years in 86 cases of bronchiectasis with hemoptysis were divided into observation and control group 2 in accordance with the digital random table method, all patients were given the antitussive, expectorant, anti infection, symptomatic and supportive treatment, observation of pituitary application group patients based on Pituitrin and phentolamine treatment, comparison two groups of patients and the total efficiency. Results In the observation group, the total effective rate was 95.3%, significantly higher than the control group of 76.7% patients, the differences between groups showed statistical significance（P〈0.05）. Observation group patients in 2 patients had abdominal pain, 2 cases of chest tightness, patients can be well tolerated, did not affect the treatment. Conclusion Pituitrin and phentolamine combined application is an ideal method for the treatment of patients with bronchiectasis with hemoptysis, should be popularized in clinic.