探讨根除幽门螺杆菌(HP)对消化性溃疡发病及复发的影响

Discussion on the Eradication of Helicobacter Pylori(HP)Effect on the Morbidity and Recurrenceof Peptic Ulcer

目的有效分析采用根除幽门螺杆菌的治疗对消化性胃溃疡患者的发病率以及病情复发情况的影响。方法选取近10年在我院行胃镜检查被被确诊为消化性溃疡的40例患者作为本次研究的观察对象,采取泮托拉唑+阿莫西林+左氧氟沙星药物联合治疗,观察患者在治疗后消化性溃疡的发病以及复发的情况。结果在有效实施根除治疗后,35例患者根除成功,根除率为87.5%,且在被给予了相关的抗溃疡药物的常规剂量治疗1个疗程后胃镜复查,18例治愈,治疗总有效率为85.71%,而半年后仅有1例复发,复发率为3.33%。而另外5例根除失败的患者同样被给予常规药物治疗后仅有2例治愈,其治疗有效率为40%,且在半年后有1例复发,复发率为50%。结论采用根除HP的治疗方法实施对PU患者的治疗,将可大大的提高患者的治疗有效率,并降低患者的复发率,值得在临床上推广与应用。

Objective To effectively analyze the effect of treatment of Helicobacter pylori eradication on morbidity in patients with peptic ulcer and disease recurrence. Methods In recent 10 years in our hospital for gastroscopy was diagnosed as peptic ulcer in 40 patients as the research object of observation, taking the combined therapy with pantoprazole amoxicillin and levofloxacin, observed in patients with peptic ulcer and recurrence situations before and after the treatment. Results Tn the effective implementation of eradication therapy, 35 patients successfully eradicate, eradication rate was 87.5%, and was given conventional dose related anti ulcer drugs after 1 courses of treatment, endoscopic examination, 18 cases were cured, the total effective rate was 85.71%, and after half a year only 1 case of recurrence, the recurrence rate was 3.33%. While the other 5 cases with eradication failure patients also were given routine therapy after only 2 cases were cured, the cure rate of 40%, and 1 cases of recurrence in half a year later, the recurrence rate was 50%. Conclusion The eradication therapy method of HP to treat PU patients, will greatly improve the treatment efficiency, and reduce the recurrence rate, worthy of clinical popularization and application.