甘露醇在重症手足口病中应用时机的探讨

Application Timing of Mannitol in Patients with Severe Hand Foot Mouth Disease

目的对甘露醇在重症手足口病患者中的早期应用效果观察。方法临床选取我院在2013年7月至2014年7月实施治疗的88例重症手足口病患者,并将其均分成两组,其中对照组患者实施常规治疗,观察组患者在常规治疗基础上加上早期甘露醇治疗,对比分析两组患者的临床治疗效果。结果和对照组相比,观察组患者的临床治疗总有效率明显偏高,差异显著(P<0.05);观察组患者的临床抖动或者惊跳时间、退热时间、脑膜刺激征消失时间以及住院时间明显少于对照组,差异显著(P<0.05)。结论在重症手足口病患者临床治疗中,对甘露醇早期应用,能够对患者的临床症状明显改善,从而取得良好临床效果,值得推广应用。

Objective To observe the application effect of mannitol in the early in patients with severe hand foot and mouth disease. Method Clinically selected patients in our hospital 88 cases of severe hand foot mouth disease, treatment implementation in July 2013-July 2014.which were divided into two groups, which control the implementation of routine treatment group, the patients in observation group on the basis of conventional therapy plus early mannitol treatment, clinical treatment effect was compared between the two groups of patients. Result Compared with the control group, to observe the clinical patients in the treatment group total effectiveness is significantly higher, difference was significant（P〈0.05）; The observation group patients clinical jitter or start time, cooling time, meningeal irritation sign disappear time of hospitalization and significantly less than the control group, the difference was significant（P〈0.05）.Conclusion In severe hand foot mouth disease in clinical treatment, the early application of mannitol, to the patient＇s clinical symptoms improved significantly, which achieved good clinical effect, it is worthy of popularization and application.