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磁共振弥散加权成像在胃癌诊断中的应用价值

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摘要 目的:探讨磁共振(MR)弥散加权成像(DWI)在胃癌诊断中的价值。方法收集临床病理确诊的胃癌患者38例作为观察组;另随机选取健康人群20例作为对照组。所有患者均在治疗前行常规磁共振成像(MRI)扫描及DWI扫描(弥散敏感因子b值取800)。利用计算机软件直接测量肿瘤组织的表观弥散系数(ADC)值及信号强度值,取其平均值。同样的方法获得对照组胃壁的ADC值及信号强度值。采用常规MRI扫描及DWI扫描与病理结果进行对比研究分析。结果病变部位胃壁明显不规则增厚,常规MR胃癌检出敏感性为92%(35/38);DWI成像胃癌原发病灶检出的敏感性为100%(38/38)。DWI上病灶部位信号强度值明显高于对照组,胃癌病灶平均信号强度值为(335.36±172.20),正常组胃壁平均信号强度值为(148.10±39.34);在b值为800时,胃癌患者病灶平均 ADC值是(0.93±0.07)215;10-3mm2/s,正常胃壁平均 ADC值是(1.78±0.08)215;10-3mm2/s,肿瘤组织ADC值明显小于正常胃壁组织;胃癌与正常胃壁的平均信号强度值及ADC值两者之间差异有统计学意义(P<0.05)。结论磁共振弥散加权成像及其ADC值在胃癌的正确诊断中具有较明显的应用价值。
出处 《浙江临床医学》 2014年第12期1986-1987,共2页 Zhejiang Clinical Medical Journal
基金 杭州市科技局医疗卫生及重点专科专病科研攻关专项基金(编号:20120633B09)
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