反应介质对聚多巴胺纳米粒子制备的影响

Effects of Reaction Medium on the Synthesis of Polydopamine Nanoparticles

采用溶液氧化法,在不同反应介质中合成聚多巴胺纳米粒子(PDA NPs)。利用紫外-可见分光光度计、红外光谱、透射电镜、粒径分析仪等手段对PDA NPs的化学结构、形貌和尺寸等进行表征。考察了不同反应介质对PDA NPs形貌和尺寸的影响。研究表明,多巴胺在氢氧化钠溶液、氨水、三羟甲基氨基甲烷(Tris)缓冲液、磷酸缓冲液等反应介质(pH=8.5)中均能制备出稳定的PDA NPs,并在溶液中表现出很好的分散性。

The effects of reaction medium on the morphologies and sizes of the synthesized polydopamine nanoparticles （PDA NPs） were reported. The PDA NPs were prepared in different reaction medias inclu- ding NaOH solution, Tris buffer solution, ammonia solution and phosphate buffer solution, respectively. The obtained PDA NPs were characterized by Fourier Transform Infrared （FF-IR） spectroscopy, Dynamic Light Scattering （DLS）, Ultraviolet （UV-vis） spectrophotometry, Transmission Electron Microscopy （TEM）. The effects of reaction medium on the morphologies and sizes of the synthesized PAD NPs were ivestigated in detail. The experimental results showed PDA NPs were successfully synthesized in these reaction media at pH 8.5. The synthesized NPs were dispersed in the reaction media uniformly.