气管插管救治急性重度有机磷中毒52例临床分析

CLINICAL ANALYSIS OF ENDOTRACHEAL INTUBATION IN 52 CASES OF ACUTE SEVERE ORGANOPHOSPHORUS POISONING

目的探讨气管插管在抢救急性重度有机磷中毒(ASOPP)患者的临床应用价值。方法回顾性分析2012年6月—2014年6月该院收治的52例行紧急气管插管后洗胃的急性重度有机磷中毒患者的临床资料,并与2010年5月—2012年5月收治的34例未实施气管插管的急性重度有机磷中毒患者临床资料进行对比观察。结果观察组52例患者中治愈47例,死亡2例,为多器官功能衰竭,自动放弃治疗3例,救治成功率为90.38%,明显高于对照组的58.82%;观察组入住重症监护室时间为(10.5±2.5)d,明显短于对照组的(15.7±3.9)d,差异具有统计学意义(P<0.05)。结论气管插管是救治急性重度有机磷中毒患者的有效措施,对于提高该类患者救治的成功率具有重要意义。

Objective To evaluate the clinical application of tracheal intubation salvage value in acute severe organophosphorus pesticide poisoning （ASOPP） patients .Methods The clinical data of 52 cases of emer‐gency endotracheal intubaion severe organophosphorus poisoning were analyzed retrospectively in June 2012 to June 2014 in author＆#39;s hospital ,meanwhile clinical data of 34 cases from May 2010 to May 2012 were ad‐mitted for acute non tracheal intubation severe organic phosphorus poisoning patients were observed and compared .Results In the observation group ,47 patients were cured ,2 cases of death with multiple organ failure ,3 cases of automatically give up the treatment ,the success rate of cure was 90 .38% ,significantly higher than that in control group 58 .82% .The ICU time in the observation group was （10 .5 ± 2 .5）d ,sig‐nificantly shorter than that in the control group （15 .7 ± 3 .9）d ,the difference was statistically significant （P〈0 .05） .Conclusion Endotracheal intubation is an effective measure for the treatment of patients with acute severe organophosphorus poisoning ,it has a vital significance for improving the treatment of the pa‐tients with successful rate .