Hcy与脑梗死牛津郡社区卒中项目分型的关系及护理干预对Hcy的影响

RELATIONSHIP BETWEEN HOMOCYSTEINE AND CEREBRAL OXFORSHIRE COMMUNITY STROKE PROJECT CLASSIFICATION AND EFFECT OF NURSING INTERVENTION

目的探讨急性脑梗死患者同型半胱氨酸(Hcy)与脑梗死牛津郡社区卒中项目(OCSP)分型的关系及护理干预对Hcy的影响。方法急性脑梗死患者236例按OCSP分型分为完全前循环梗死(TACI)型26例、部分前循环梗死(PACI)型76例、后循环梗死(POCI)型42例和腔隙性梗死(LACI)型92例,并进行护理干预,入院及2个月后检测Hcy水平,分析Hcy与急性脑梗死OCSP分型的关系,观察护理干预对Hcy的影响。结果 1TACI、POCI组Hcy高于LACI组,差异有统计学意义(P<0.05)。2进行护理干预后脑梗死患者Hcy较干预前明显下降,差异有统计学意义(P<0.05)。结论 Hcy与急性脑梗死OCSP分型相关,护理干预可降低Hcy水平。

Objective To analyze the relationship between hyperhamccysteiinemia and the Oxforshire Com‐munity Stroke Project（OCSP） types in patients with acute cerebral infarction ,and to observe the effect of nursing intervention .Methods A total of 236 patients with acute cerebral infarction were classified into four subtypes by OCSP such as total anterior circulation infarct （TACI ,n=26） ,partial anterior circulation infarction （PACI ,n= 76） ,posterior circulation infarction （POCI ,n= 42） and lacunar cerebral infarction （LACI ,n=92） .A nursing intervention was performed for all subjects and whose hyperhamccysteiinemia levels was detected at before and two months after nursing intervention ,then the relationship between hy‐perhamccysteiinemia and OCSP classification in patients of acute cerebral infarction was observed .Results Hyperhamccysteiinemia in TACI group and POCI group were all higher than LACI group ,the differ‐ences were statistical significance （F= 6 .912 ,P〈 0 .05） .Compared with before intervention ,the hyper‐hamccysteiinemia in patients with cerebral infarction was significantly decreased after nursing intervention , the difference was statistically significant （t=3 .29-6 .82 ,P〈0 .05） .Conclusions Hyperhamccysteiinemia is related to subtypes TACI and POCI of OCSP in acute cerebral infarction .Nursing intervention can reduce Hyperhamccysteiinemia .