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TOAST分型下脑梗死患者急性期血压调控对预后的影响

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摘要 目的探讨TOAST分型下脑梗死患者急性期血压调控对预后的影响。方法168例明确诊断为脑梗死急性期(发病24h内)患者按照是否进行血压干预分为血压干预组(n=65)及对照组(n=103),对照组进行常规对症支持性治疗,血压干预组在对照组基础上进行降血压治疗,使患者入院1d内的血压下降至160/100mmHg内,采用NIHSS、Barthd Index及改良Rankin评价表比较两组患者入院时、治疗第1周、治疗半年的评分状况。结果两组患者人院时及治疗第1周时的NIHSS评分、Barthd Index评分及改良Rankin评分两两比较差异无统计学意义(P〉0.05);血压干预组治疗半年后的BarthelIndex评分显著低于对照组同期水平(54.6±16.3VS66.3±18.7)(P〈0.05),而NIHSS评分(15.3±4.1vs13.9±3.7)及改良Rankin评分(1.4±0.9VS1.2±0.8)显著高于对照组同期水平,差异有统计学意义(P〈0.05)。TOAST下各型患者入院时、治疗1周后及治疗半年后的NIHSS评分、Barthel Index评分及改良Rankin评分两两比较差异有统计学意义(P〈0.05),入院时、治疗1周后及治疗半年后CE患者的NIHSS评分、Barthd Index评分与其它各型同一评分比较差异有统计学意义(P〈0.05);入院时、治疗1周后CE患者Rankin评分显著高于其它各型(P〈0.05)。结论脑梗死急性期患者急切的将血压调控至60/100mmHg内,将降低患者预后状况,TOAST分型下的脑梗死患者血压干预患者中以CE及LAA型预后相对较差,SAO及SUE型预后较好。
机构地区 高要市人民医院
出处 《国际医药卫生导报》 2015年第2期161-163,共3页 International Medicine and Health Guidance News
基金 肇庆市科技创新计划项目(2012E2110)
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