冠心病血瘀证与慢性炎症因子相关性临床研究

Clinical Research on Correlativity between CHD Blood Stasis Syndrome and Chronic Inflammatory Factors

目的:研究冠心病血瘀证与hs-CRP及s ICAM-1的相关性,从动脉粥样硬化慢性炎性探讨冠心病血瘀证的病理本质。方法:选择26例冠心病血瘀证患者、32例冠心病非血瘀证患者及30例健康人,根据其hs-CRP、s ICAM-1检测结果,研究其与冠心病血瘀证的相关性。结果:冠心病各证型患者血液中hs-CRP和s ICAM-1水平明显高于健康人,其中以血瘀证患者hs-CRP和s ICAM-1水平最高(P<0.05)。结论:动脉粥样硬化慢性炎性病变过程可能在冠心病血瘀证的形成中扮演重要角色,应进一步探索研究。

Objective： To research the correlativity between CHD blood stasis syndrome and hs-CRP,s ICAM-1,so as to explorate the pathological nature of CHD blood stasis syndrome from chronic inflammatory of atherosclerosis. Method： To select 26 cases of patients with CHD blood stasis syndrome,32 cases of patients with CHD non blood stasis syndrome and 30 cases of healthy persons. According to the detceted results of their hs-CRP and s ICAM-1,to research the correlativity between hs-CRP,s ICAM-1 and CHD blood stasis syndrome. Result： hs-CRP and s ICAM-1 levels in blood of patients with CHD different syndrome types were significantly higher than in healthy people. Among them,hs- CRP and s ICAM-1 levels of patients with blood stasis syndrome were highest（ P〈0. 05）. Conclusion： The pathological changes process of chronic inflammatory of atherosclerosis may play an important role in the formation of CHD blood stasis syndrome,which is worth further explorating and researching.