摘要
建立了地奥心血康胶囊中甾体皂苷类成分的高效液相色谱指纹图谱。采用Inersil ODS-3 C18柱,以乙腈:0.1%甲酸为流动相,梯度洗脱,使用蒸发光散射检测器检测。共检测11批地舆心血康胶囊,建立其甾体皂苷成分指纹图谱的共有模式,相似度为0.934~0.998。确定8个共有峰,并利用对照品对照法指认其中的2个共有峰成分,即原薯蓣皂苷和薯蓣皂苷。
The fingerprint of steroid saponins from Di'aoxinxuekang capsules was established by HPLC-ELSD method, An Inersil ODS-3 column was used, with the mobile phase of acetonitrile :0.1% formic acid by gradient elution, with the application of evaporative light scattering detector (ELSD). The common pattern fingerprint of steroid saponins was established after examining 11 batches of Di'aoxinxuekang capsules, and their similarities were 0.934 - 0.998. There were 8 common peaks, in which two of them were identified as protodioscin and dioscin using the reference compounds.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2015年第1期65-67,共3页
Chinese Journal of Pharmaceuticals