温和条件下钒催化氧化胺、醇和胺直接合成亚胺(英文)

Vanadium catalyzed direct synthesis of imines from amines or alcohols and amines by an aerobic oxidative reaction under mild conditions

开发了钒催化氧化胺、醇和胺直接合成亚胺催化体系,无须额外的添加剂或促进剂,空气作为环境友好的氧源,温和条件下,能高收率地得到各种对称和非对称亚胺,并且催化剂非常容易制备和使用.该催化体系对含杂原子亚胺的合成也非常有效.

The direct synthesis of imines from amines or alcohols and amines by vanadium catalyzed aerobic oxidation was developed. Without an additive or promoter, various symmetrical and unsymmetrical imines were obtained in good to excellent yields under mild conditions with air as an environmen-tally benign oxidant. The catalyst is very easy to prepare and use, and this catalytic system is also effective for the synthesis of heteroatom-containing imines.