摘要
结合绿色化学概念,将酮肟还原酰化和末端炔氧化偶联在一锅进行反应,发展了一种Pd/Cu协同催化一锅绿色合成烯酰胺和1,3-二炔的新方法.该方法无需外加任何氧化剂和还原剂,可同时得到烯酰胺和1,3-二炔,产率高,反应条件温和.
A green organic synthetic method combining reductive acylation of ketoximes and oxidative cou-pling of terminal alkynes was developed. This novel process enables enamides and 1,3-diynes to be synthesized simultaneously in high yields and under mild conditions without the use of terminal reductants/oxidants.
出处
《催化学报》
SCIE
EI
CAS
CSCD
北大核心
2015年第1期113-118,共6页
基金
supported by the National Natural Science Foundation of China (21272183)
the Fund of the Rising Stars of Shaanxi Province (2012KJXX-26)~~
关键词
绿色合成
酮肟
末端炔
烯酰胺
1
3-二炔
Green synthesis Ketoxime Terminal alkyne Enamide 1
3‐Diyne
