养阴通络丸联合针刺治疗脑梗死后遗症的临床疗效观察

Clinical Observation of Yangyin Tongluo Pills Combined with Acupuncture for Treatment of Cerebral Infarction Sequela

【目的】观察养阴通络丸联合针刺治疗脑梗死后遗症的临床疗效。【方法】将100例脑梗死后遗症患者随机分为治疗组和对照组各50例。对照组给予常规针刺并口服氯吡格雷治疗,治疗组在常规针刺基础上加用养阴通络丸(枸杞子、菊花、生地黄、牡丹皮、丹参、红花、桃仁、地龙、天麻、钩藤、夏枯草、沙参、麦冬、五味子、太子参等)治疗,1个月为1个疗程,共治疗2个疗程。观察2组临床疗效及治疗前后神经功能缺损程度评分(NIHSS)、Barthel日常生活活动能力(ADL)指数评分及血液流变学指标的变化。【结果】(1)经2个疗程治疗,2组均可降低NIHSS评分,提高ADL指数评分(P<0.01),且治疗组的改善程度均优于对照组(P<0.01)。(2)治疗后,治疗组的各项血液流变学指标均明显改善(P<0.05或P<0.01),而对照组各项血液流变学指标治疗前后均无明显改变(P>0.05),治疗组对各项血液流变学指标的改善作用均优于对照组(P<0.05)。(3)治疗组总有效率为90.00%,对照组为64.00%,治疗组的总体疗效优于对照组(P<0.05)。【结论】养阴通络丸联合针刺治疗脑梗死后遗症疗效确切,其疗效优于常规针刺联合氯吡格雷治疗。

Objective To observe the clinical effect of Yangyin Tongluo Pills combined with acupuncture for the treatment of cerebral infarction sequela. Methods One hundred patients with cerebral infarction sequela were evenly randomized into treatment group and control group. The control group was given acupuncture therapy combined with oral use of clopidogrel, and the treatment group was given acupuncture therapy combined with oral use of Yangyin Tongluo Pills （mainly composed of Fructus Lycii, Flos Chrysanthemi, Radix Rehmanniae, Cortex Moutan, Radix Salviae Miltiorrhizae, Flos Carthami, Semen Persicae, Pheretima, Rhizoma Gastrodiae, Ramulus Uncariae cum Uncis, Spica Prunellae, Radix Glehniae, Radix Ophiopogonis, Fructus Schisandrae Chinensis, Radix Pseudostellariae） . One month constituted a treatment course, and the treatment covered 2 courses. After treatment, the therapeutic effect of the two groups was evaluated, and the changes of National Institute of Health Stroke Scale （ NIHSS） scores and Barthel Index Scale for activities of daily living （ ADL） , and hemorrheology indexes were observed before and after treatment. Results （1） After treatment for 2 courses, NIHSS scores were decreased, ADL scores were increased in the two groups （P0.05） . The treatment group had better effect on improving hemorrheology indexes than the control group （P〈0.05） . （3） The total effective rate of the treatment group was 90.00% and that of the control group was 64.00%, the overall therapeutic effect of the treatment group being superior to that of the control group （P〈0.05） . Conclusion Yangyin Tongluo Pills combined with acupuncture are effective for the treatment of cerebral infarction sequela, and the effect is superior to that of acupuncture combined with clopidogrel.