摘要
HBV相关慢加急性肝衰竭(ACLF)严重影响人类健康。该病病情进展较快、病死率高。如果能在患者发生ACLF之前,及时将其筛选并获得诊断,进行必要的干预和治疗,将对患者预后产生重要的影响。因此,一些学者开始重视对肝衰竭前期患者的研究。由于对疾病定义存在差异,国外和我国香港、台湾地区学者将慢性乙型肝炎严重急性发作定义为肝衰竭前期,而我国大陆也有学者尝试着制定了三种不同的慢加急性肝衰竭前期诊断标准。本文主要就ACLF前期概念及诊疗进展进行讨论。
Hepatitis B virus （HBV）-related Mute-on-chronic liver failure （ACLF）,characterized by rapid disease progres- sion and high mortality,is a serious health problem in China. The outcomes will differ if the clinicians can diagnose the patients with ACLF in time and give them instant intervention. So some scholars in the world began to study the patients in so-called pre-liver failure stage. The scholars in the west, Hong Kong and Taiwan defined it as severe acute exacerbation of chronic hep- atitis B,while the scholars in the mainland tried to set up three different diagnostic criteria for pre-ACLF. This review mainly focuses on recent advances in the definition, diagnosis and treatment of patients with HBV-related pre-ACLF.
出处
《实用肝脏病杂志》
CAS
2015年第1期105-108,共4页
Journal of Practical Hepatology
基金
"十二五"国家传染病科技重大专项(编号:2012ZX10002004-005)
关键词
乙型肝炎
肝衰竭
前期
诊断
治疗
Hepatitis B
Liver failure
Pre-stage
Diagnosis
Treatment
