卵巢交界性肿瘤行保留生育功能手术的研究进展

Advances in study of fertility-sparing surgery in borderline ovarian tumor

卵巢交界性肿瘤是一类组织病理学和生物学行为介于良性、恶性之间的卵巢肿瘤。患者多为年轻女性,尚未完成生育,病理类型以卵巢上皮性交界性肿瘤最为多见,大多临床分期早,预后好,治疗主要以手术为主,而不同手术方式的选择与患者生育功能的保留问题密切相关。本文就卵巢交界性肿瘤患者保留生育功能手术方式的选择,包括腹腔镜手术的术式,术后化疗方案,手术对妊娠的影响以及合并不孕患者促排卵药物的安全性问题进行综述。

Borderline ovarian tumors （BOT） are characterized by histopathologic features and biologic behaviors intermediate between clearly benign and frankly malignant ovarian tumors. Most patients are young, and need high fertility and the quality of life. The majority of BOT is diagnosed at early stage, the histopathological types are epithelial ovarian tumor, and their prognosis is good. This review discussed the choice of the surgical method including the laparoscopic surgery, chemotherapy after the surgery, the effect to pregnancy from the surgery and the security of ovulation drugs.