中西医结合治疗中晚期非小细胞肺癌的疗效观察

Effect Observation on Therapy Based on Chinese and Western Medicine for Advanced Non-small Cell Lung Cancer

目的通过观察中药配合化疗治疗中晚期非小细胞肺癌的临床疗效,探讨中西医结合治疗中晚期非小细胞肺癌的相对优势。方法收集符合标准的病例共338例,其中中药联合化疗组177例,化疗组161例。比较两组近期疗效,临床证候积分、KPS评分、免疫指标、体重及生存期的差异。结果中药联合化疗组和化疗组有效率分别为44.6%、40.4%(P>0.05),2组差异无统计学意义。中药联合化疗组总稳定率为81.9%、高于化疗组66.5%(P<0.05),中药联合化疗组在改善患者临床症状、提高生活质量、免疫功能及生存期方面明显优于化疗组(P<0.05),稳定体重方面(P>0.05)无明显差异。结论中药联合化疗组在稳定体重方面无优势,但其能够提高中晚期非小细胞肺癌患者的稳定率,并在一定程度上改善患者疾病相关症状,提高患者的生存质量、免疫功能及生存时间。

Objective To observe the clinical curative effect of traditional Chinese medicine combined with chemotherapy in the treatment of advanced non-small cell lung cancer,the relative advantages of combination therapy in the treatment of advanced non-small cell lung cancer with integrated traditional Chinese and Western medicine. Methods In accordance with the standards of the 338 cases,in which the Chinese medicine combined with chemotherapy group of 161 cases,177 cases of chemotherapy group.Comparison of two groups of curative effect in the near future,difference of clinical symptom score,KPS score,immune index,body weight and survival time. Results The traditional Chinese medicine combined with chemotherapy group and chemotherapy group efficiency is respectively 44.6%,40.4%（P〉0.05）,no statistically significant difference between the two groups. Traditional Chinese medicine combined with c. Traditional Chinese medicine combined with chemotherapy group was 81. 9%,higher than the overall stability of chemotherapy group and 66. 5%（P〈0.05）,TCM combined with chemotherapy group in improving clinical symptoms,improve life quality,immune function and survival time were significantly better than the chemotherapy group（P〈0.05）,stable body weight had no significant difference（P〉0.05）. Conclusion Traditional Chinese medicine combined with chemotherapy group had no advantage in the stable weight,but it can improve in patients with advanced non-small cell lung cancer stability rate,and improve patient disease-related symptoms to a certain extent,improve the quality of life of patients,immune function and survival time.