原发性甲状腺功能亢进症并发甲状腺癌分析

Analysis of primary hyperthyroidism and concurrent thyroid carcinoma

目的：探讨原发性甲状腺功能亢进症并发甲状腺癌患者诊治方法。方法对46例原发性甲状腺功能亢进症并发甲状腺癌患者行全甲状腺切除术。结果两种疾病的并存率为5．7％（46／810）。术前确诊率为10．8％（5／46）。对46例患者均行手术治疗，其中25例术中经快速冰冻切片病理学检查明确诊断，行全甲状腺切除术；21例术后病理学检查明确诊断，再次手术切除残余甲状腺。7例行颈淋巴结清扫术。术后随访6个月～10年无复发。结论原发性甲状腺功能亢进症患者需排除并发甲状腺癌可能，全甲状腺切除术治疗原发性甲状腺功能亢进症并发甲状腺癌效果良好。

Objective To study the diagnosis and treatment for patients with primary hyperthy-roidism and concurrent thyroid carcinoma.Methods A total of 46 patients with primary hyperthyroidism and concurrent thyroid carcinoma underwent total thyroidectomy.Results The coexistence proportion of the two diseases was 5.7%（46 /810）.Preoperative diagnosis rate was 10.8%（5 /46）.All the 46 patients underwent surgical treatment,including 25 cases with pathological diagnosis of intraoperative frozen section and total thyroidectomy and 21 cases with postoperative pathological diagnosis and reoperation of residual thyroid.Seven patients underwent neck lymph dissection.Patients were followed up for 6 months to 10 years without recurrence.Conclusion The possibility of thyroid carcinoma has to be excluded in patients with primary hyperthyroidism.Total thyroidectomy has beneficial effects on patients with primary hyperthy-roidism and concurrent thyroid carcinoma.