高支链氨基酸肠外营养在综合ICU重症患者中的应用研究

Application research of parenteral nutrition with high branched-chain amino acid content for criti- cally ill patients in general ICU

目的研究高支链氨基酸肠外营养在综合ICU重症患者中的应用。方法将60例综合ICU重症患者随机分成对照组（30例）和治疗组（30例），在肠外营养配方中，对照组应用平衡氨基酸，治疗组应用高支链氨基酸。对两组的治疗结果和相关血液指标进行测定。结果治疗组的总蛋白（TP）、白蛋白（ALB）、前白蛋白（PA）、上臂肌围（AMC）和上臂周径（MAC）在治疗7d后均有明显提高（P〈0．05）；对照组仅有TP、ALB、PA在治疗7d后的变化差异有统计学意义（P〈0．05）；治疗组比对照组的营养改善更加显著。结论在综合ICU重症患者中应用高支链氨基酸肠外营养能够为患者提供有效的营养支持，且无相关副作用。

Objective To research the effects of parenteral nutrition （PN）with high branchedchain amino acid （BCAA） content for critically ill patients in general ICU. Methods A total of 60 patients from the general ICU were randomly divided into the control group（ 30 cases）and treatment group（ 30 ca- ses）. The control group was given PN with balanced amino acids, while the treatment group received PN with high content of BCAA. Therapeutic outcomes and the blood parameters were measured between groups. Results Total protein （ TP ） , albumin （ ALB ）, prealbumin （ PA ）, arm muscle circunfference （AMC） and arm circumference （ MAC ） of the treatment group increased significantly （ P 〈 0.05 ）. In the control group, the change of TP, ALB and PA after 7 days was statistically significant （ P 〈 0.05 ）. Compared to the control group, the improvement of parameters in the treatment group was more obvious. Conclusion For patients in general ICU, parenteral nutrition with high BCAA content is able to provide effec- tive nutritional support without relative side-effects.