核磁共振法定量影响因素探析

Discussion on the Factors Influencing Quantitative Nuclear Magnetic Resonance Determination

定量核磁共振技术作为一种定量分析方法,具有操作容易,样品制备简单,非破坏性,分析时间短,专属性强,准确度高等优点,可以作为质量平衡定值方法的一种有力补充。定量核磁共振方法有很多种,例如1H-q NMR,13C-q NMR,19F-q NMR和31P-q NMR等,1H-q NMR是最广泛使用的。核磁定量结果的影响因素有很多,最主要的干扰因素为定量样品制备,核磁共振实验参数设定,数据处理参数设定等,本文将详细讨论影响核磁定量结果的因素。

Quantitative nuclear magnetic resonance （ qNMR） is a well-known quantitative analytical technique.It＆amp;nbsp;has great advantages,such as easy-operation,simple sample-preparation,non-destructive sample,a relatively short a-nalysis time,high specificity and accuracy,etc.It can be used as a good supplement for mass balance method.QN-MR has many kinds, such as ^1H-qNMR,^13C-qNMR,^19F-qNMR and ^31P-qNMR.^1H-qNMR is the most commonly used.Accuracy of qNMR is affected by a lot of factors,including sample preparation,parameter setting for data ac-quisition,processing and analysis.All influence factors will be discussed in this paper.