针药联合治疗糖尿病周围神经病变的临床观察

Clinical observation on treating diabetic peripheral neuropathy by acupuncture plus medicine

目的:研究针刺联合中成药口服治疗糖尿病周围神经病变的疗效。方法:将符合纳入标准的80例糖尿病周围神经病变的患者随机分为治疗组与对照组,每组40例,治疗组采用针刺及口服中成药天丹通络胶囊进行治疗,对照组口服弥可保片,治疗前后分别对血生化、血常规、双侧腓总神经传导速度进行检测评价,并对中医证候及神经系统症状及体征进行评分记录评估。结果:治疗前后,两组患者在血生化、血细胞分析、糖化血红蛋白等理化指标方面比较无差异(P>0.05),中医症候积分、神经系统症状及体征积分、神经传导速度方面有显著差异(P<0.05);经过治疗后,与对照组比较,治疗组在血生化、血细胞分析、糖化血红蛋白等理化指标方面比较无差异(P>0.05),而在中医证候积分,双侧腓总神经传导速度及疗效方面有显著差异(P<0.05)。结论:针刺及化瘀通络中药联合治疗能有效改善糖尿病周围神经病变,疗效优于西药营养神经类制剂,有利于临床推广应用中医综合治疗糖尿病周围神经病变。

Objective： To research clinical effects of acupuncture plus TCM medicine on diabetic peripheral neuropathy. Methods： 80 patients were randomly divided into two groups, 40 cases for each, the treatment was given the acupuncture plus Tiandan Tongluo capsule, while the control was given Methycobal. Blood chemistry, blood, bilateral peroneal nerve conduction velocity before and after treatment were detected, TCM syndromes and neurological symptoms and signs were scored. Results： In two groups, index-of blood chemistry, blood, bilateral peroneal nerve conduction velocity show no difference （P〉0.05）; symptom scores, neurological symptoms and signs of integration, nerve conduction velocity has great difference （P〈0.05）; after treatment, index of blood chemistry, blood cell analysis, glycated hemoglobin in the treatment show no difference （P〉0.05）; while index of TCM syndrome score, aspects of bilateral peroneal nerve conduction velocity and efficacy were in the contrary （P〈0.05）. Conclusion： Acupuncture plus Huayu Tongluo capsule can effectively improve diabetic peripheral neuropathy, and were worthy of application and better than western neurotrophic preparations.