小儿清肺颗粒治疗儿童急性支气管炎临床观察

Clinical observation on treating acute bronchitis in children with Xiao'er Qingfei particle

目的:观察小儿清肺颗粒治疗儿童支气管炎的临床疗效。方法:将2013年9月-2014年3月在河南省中医院门诊治疗的120例儿童支气管炎患儿随机分为治疗组60例、对照组60例。两组均根据具体情况给予抗感染治疗(据患儿的感染指标、支原体检查结果分别给予头孢克洛20~40mg·kg^(-1)·d^(-1),分3次口服或阿奇霉素10mg·kg^(-1)·d^(-1),1次/d口服或利巴韦林10~15mg·kg^(-1)·d^(-1),分3次口服),发热者加用小儿柴桂退热颗粒(1岁以内,2.5g/次,3次/d;1~3岁,5g/次,3次/d;4~6岁,7.5g/次,3次/d)口服,治疗组加用小儿清肺颗粒口服;疗程5~7d,疗程结束后比较两组的疗效及不良反应。结果:治疗组在疗效上优于对照组(P<0.05);治疗组的退热时间,咳嗽、咳痰消失时间,哕音消失时间,平均治愈时间均短于对照组,差异有统计学意义(P<0.05);不良反应上两组差异无统计学意义。结论:应用小儿清肺颗粒治疗儿童支气管炎疗效肯定,不良反应少,值得临床推广。

Objective： To observe clinical efficacy ofXiao＇er Qingfei particle on acute bronchitis in children. Methods： 120 patients in our hospital were randomly divided into the treatment group （60 cases） and the control group （60 cases） from Sept. 2013 to March 2014. The two groups received antibiotics treatment （20-40mg · kg^-1 · d^-1 cefaclor was given based on infectious indexes and Mmycoplasma test results in children, 3 times orally; or 10mg · kg^-1 · d^-1 azithromycin, qd; or 10-15mg · kg^-1 · d^-1 ribavirin, 3 times orally ）; patients with fever were added Xiao＇er Chaigui Tuire particle orally （ within 1 year old, 2.5g per time, tid; 1-3 years old, 5g per time, tid; 4-6 years old, 7.5g per time, tid）; the treatment group was given Xiao＇er Qingfei particle more, 5-7d for 1 course. Clinical effects and adverse reaction in two groups were compared after treatment. Results： Clinical efficacy in the treatment group was better （P〈0.05）; antipyretic time, cough, expectoration disappearing time, tale disappearing time and the average healing time in the treatment group were shorter, the difference was statistically significant （P〈0.05）. There was no statistically significance on adverse reaction. Conclusion： Xiao＇er Qingfei particle was confirmed with good clinical efficacy and less adverse reaction, and was worthy of clinical promotion.