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An environmentally friendly synthesis of 1,4-dihydropyrano[2,3-c]pyrazole derivatives catalyzed by tungstate sulfuric acid 被引量:2

An environmentally friendly synthesis of 1,4-dihydropyrano[2,3-c]pyrazole derivatives catalyzed by tungstate sulfuric acid
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摘要 An efficient three-component synthesis of 6-amino-4-aryl-5-cyano-3-metriyl-1-phenyl-1,4-dihydropyrano[2,3-c]pyrazoles via a reaction between 3-methyl-1-phenyl-2-pyrazolin-5-one,aromatic aldehydes and malononitrile using tungstate sulfuric acid as a catalyst was described.Mild conditions,good to excellent yields,easily available catalyst and easy work-up are the key features of this method. An efficient three-component synthesis of 6-amino-4-aryl-5-cyano-3-metriyl-1-phenyl-1,4-dihydropyrano[2,3-c]pyrazoles via a reaction between 3-methyl-1-phenyl-2-pyrazolin-5-one,aromatic aldehydes and malononitrile using tungstate sulfuric acid as a catalyst was described.Mild conditions,good to excellent yields,easily available catalyst and easy work-up are the key features of this method.
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2014年第12期1580-1582,共3页 中国化学快报(英文版)
关键词 6-Amino-4-aryl-5-cyano-3-methyl-1phenyl-1 4-dihydropyrano[2.3-c]pyrazoles 3-Methyl-1-phenyl-2-pyrazolin-5-one Aromatic aldehyde Malononitrile Tungstate sulfuric acid 6-Amino-4-aryl-5-cyano-3-methyl-1phenyl-1,4-dihydropyrano[2.3-c]pyrazoles 3-Methyl-1-phenyl-2-pyrazolin-5-one Aromatic aldehyde Malononitrile Tungstate sulfuric acid
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