期刊文献+

Synthesis and properties of poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/chitin nanocrystals composite scaffolds for tissue engineering 被引量:2

Synthesis and properties of poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/chitin nanocrystals composite scaffolds for tissue engineering
原文传递
导出
摘要 Poly(3-hydroxybutyrate-co-3-hydroxyvalerate)(PHBV)/chitin nanocrystals(CNC) composite scaffolds were synthesized by the salt leaching and thermally induced phase separation(TIPS) technique.The scaffolds have porous structures with macro-pores(100-300 μm in diameters) and micro-pores(10μm).The surface characteristics of the scaffolds were characterized by X-ray photoelectron spectroscopy(XPS) and static water contact angle measurement,and the mechanical properties were investigated by a compression test.Human adipose-derived stem cells(hADSCs) were seeded onto the PHBV/CNC scaffolds and in vitro cell culture results showed that the composite scaffolds enhanced the hADSCs adhesion,which implies that the material may have potential application in tissue engineering. Poly(3-hydroxybutyrate-co-3-hydroxyvalerate)(PHBV)/chitin nanocrystals(CNC) composite scaffolds were synthesized by the salt leaching and thermally induced phase separation(TIPS) technique.The scaffolds have porous structures with macro-pores(100-300 μm in diameters) and micro-pores(10μm).The surface characteristics of the scaffolds were characterized by X-ray photoelectron spectroscopy(XPS) and static water contact angle measurement,and the mechanical properties were investigated by a compression test.Human adipose-derived stem cells(hADSCs) were seeded onto the PHBV/CNC scaffolds and in vitro cell culture results showed that the composite scaffolds enhanced the hADSCs adhesion,which implies that the material may have potential application in tissue engineering.
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2014年第12期1635-1638,共4页 中国化学快报(英文版)
基金 Ministry of Science and Technology of the People's Republic of China(No.1106) Ningbo Science Foundation (No.2011A610116) National Key Basic Research Program of China(973,No.2014CB643305) the China Postdoctoral Science Foundation Funded Project(No.2012T50564) for financial support
关键词 PHBV Chitin nanocrystals Composite scaffolds hADSCs PHBV Chitin nanocrystals Composite scaffolds hADSCs
  • 相关文献

参考文献34

  • 1R. Cancedda, B. Dozin, P. Giannoni, R. Quarto, Tissue engineering and cell therapy of cartilage and bone, Matrix Biol. 22 (2003) 81-91.
  • 2R. Langer, D.A. Tirrell, Designing materials for biology and medicine, Nature 428(2004) 487-492.
  • 3P. Lichte, H.C. Pape, T. Pufe, P. Kobbe, H. Fischer, Scaffolds for bone healing: concepts, materials and evidence, Injury 42 (2011) 569-573.
  • 4L.B. Rocha, G. Goissis, M.A. Rossi, Biocompatibility of anionic collagen matrix as scaffold for bone healing, Biomateriais 23 (2002) 449-456.
  • 5H.J. Jin, J. Chen, V. Karageorgiou, G.H. Altman, D.L. Kaplan, Human bone marrow stromal cell responses on electrospun silk fibroin mats, Biomaterials 25 (2004) 1039-1047.
  • 6F. Zhang, F. Mei, X.Z. Wang, et al., A new route for preparation of p-TCP/PLLA composite. Chin. Chem. Lett. 17 (2006) 883-886.
  • 7J.M. Williams, A. Adewunmi, R.M. Schek, et al., Bone tissue engineering using polycaprolactone scaffolds fabricated via selective laser sintering, Biomaterials 26(2005)4817-4827.
  • 8A.S. Goldstein, T.M. Juarez, C.D. Helmke, M.C. Gustin, A.G. Mikos, Effect of convection on osteoblastic cell growth and function in biodegradable polymer foam scaffolds, Biomateriais 22 (2001) 1279-1288.
  • 9D. Puppi, F. Chiellini, A.M. Piras, E. Chiellini, Polymeric materials for bone and cartilage repair. Prog. Polym. Sci. 35 (2010) 403-440.
  • 10G.Q. Chen, Q. Wu, The application of polyhydroxyalkanoates as tissue engineering materials, Biomateriais 26 (2005) 6565-6678.

同被引文献2

引证文献2

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部