住院肿瘤患者免疫调节药物处方点评应用实践

Clinical Practice of Prescription Evaluation of Immunomodulatory Drugs Used in Tumor Inpatient

目的:建立科学化、标准化的肿瘤患者免疫调节药物处方点评模式,提高住院肿瘤患者免疫调节药物临床合理用药水平。方法:回顾性调查分析我院2012-2013年658份肿瘤患者住院医嘱,对其免疫调节药物的使用情况进行评价,归纳免疫调节药物评价指标和评价标准,建立免疫调节药物点评模式。结果:抽取的658份医嘱中,合格医嘱为495份,适应证及用法、用量适宜,合格率为75.2%;不合格医嘱为163份,多数为无适应证和超剂量使用,另有少部分为给药途径及稀释溶媒不适宜,不合格率为24.8%。结论:通过对住院肿瘤患者应用免疫调节药物的处方点评和分析,初步构建肿瘤辅助药物的评价体系。通过此体系的临床实践,使我院处方的不合格率明显降低。

Objective：To set up a scientific and standardized prescription evaluation mode for tumor patients using immunomodulatory drugs, and to improve the level of clinical rational use of immunomodulatory drugs in tumor inpatients in hospital.Methods：A retrospective investigation and analysis were conducted of 658 pieces of medical orders of cancer patients in our hospital from 2012 to 2013,the application of immunomodulatory drugs was evaluated, the evaluation index and criteria were summed up,and an evaluation mode for the rational use of immunomodulatory drugs was established.Results：Among 658 medical orders 495 pieces（75.2%）were qualified with appropriate drug indications, usage and dosage, 163 pieces（24.8%）were unqualified and most of the prescriptions with no indications and overdose,or with inappropriate route of administration and dilution solvent. Conclusion：Through the prescription review and analysis of immunomodulatory drugs for hospitalized cancer patients,the evaluation system of tumor auxiliary drugs was preliminary established, and through practice with this system, unqualified prescription was significantly reduced.