急性肝炎胆囊内胆汁淤积症的超声研究

Study of Acute Hepatitis with Gallbladder Sludge by Sonography

目的:探讨由急性肝炎引起的胆囊内胆汁淤积症的超声特点及临床意义。方法:对急性肝炎伴胆囊内胆汁淤积症患者54例,行超声检查并随访,同时设置对照组34例。两组患者的丙氨酸氨基转移酶(Alanine aminotransferase,ALT)、总胆红素(Total Bilirubin,TBi L)均显著高于无胆汁淤积组(P=0.012,P=0.006)。结果:随着肝功能的好转,54例患者中,49例患者胆囊内的胆汁淤积症消失,3例患者淤积的胆汁缩小成团,回声逐渐增高,1例呈高回声团经胆管排出,1例患者形成结石。且胆囊恢复时间较无胆汁淤积组长(P=0.000 1)。结论:急性肝炎胆囊内胆汁淤积症患者肝功能损害重,病程长,超声连续观察有助于指导临床治疗。

Objective：To assess the characteristics and clinical significance of sonography applied on patients with gallbladder sludge induced by acute hepatitis. Methods：54 cases with acute hepatitis with gallbladder sludge were ex-amined and followed up by sonography,and then the control group of 34 cases without gallbladder sludge were com-pared. Alanine aminotransferase（ALT）and total bilirubin（TBiL）in the group of acute hepatitis with gallbladder sludge were significantly higher than that of control group（ P=0 . 012 ,P=0 . 006 ）. Result：With the improvement of liver function,of 54 patients,gallbladder sludge disappeared in 49 patients;the bile sludge lessened in 3 patients and echo gradually increased;1 cases with high echoes was discharged through the common bile duct;the formation of stones was observed in 1 patient and the recovery time was longer than that of control group（ P=0 . 0001 ）. Conclusion：Based on the fact that Liver function damage is severer in patients with acute hepatitis with gallbladder sludge and course of dis-ease is longer,Ultrasonic continuous observation is helpful in guiding clinical treatment.