摘要
目的观察改良DCF方案治疗晚期胃癌的临床疗效及毒副反应。方法 33例患者均经病理及影像学确诊为转移或复发性晚期胃癌,给予改良DCF方案化疗,至少完成2个周期治疗后评估临床疗效及不良反应。结果完全缓解(CR)1例,部分缓解(PR)16例,有效率(CR+PR)为51.5%。主要不良反应有骨髓抑制,恶心、呕吐、腹痛、腹泻等消化道反应。结论改良DCF方案治疗晚期胃癌临床疗效较好,毒副反应可耐受。
Objective To observe the efficacies and toxicities of the modified DCF regime in the treatment of advanced gastric cancer .Methods Thirty-three patients with advanced gastric cancer , diagnosed by histopathology and imaging, were treated with the modified DCF regime .Each patient received at least 2 cycles of the treatment . The efficacies and toxicities were evaluated after treatment .Results Among thirty-three patients ,the overall response rate was 51.5%（CR in 1 patients,PR in 16 patients）.The main toxicities were myelosuppression and gastrointestinal reactions .Conclusion The effect of the modified DCF regime in the treatment of advanced gastric cancer is better , and the toxicities are tolerable .
出处
《中国临床新医学》
2014年第12期1132-1133,共2页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
关键词
改良DCF方案
化疗
晚期胃癌
Modified DCF regime
Chemotherapy
Advanced gastric cancer
