中西药口服联合保留灌肠治疗溃疡性结肠炎的临床研究

Chinese Herbal and Western Medicine for Oral Administration and for Retention Enema in the Treatment of Ulcerative Colitis

为探讨中西药口服联合保留灌肠治疗溃疡性结肠炎（UC）的临床疗效，回顾我科采用此方法（38例，观察组）和单纯采用中西药口服法（30例，对照组）治疗UC患者的疗效，并进行对比分析。结果显示，观察组痊愈12例，显效18例，有效7例，无效1例，总有效率为97．4％（37／38）；对照组痊愈8例，显效12例，有效6例，无效4例，总有效率为86．7％（26／30）。观察组总有效率明显高于对照组，P〈0．05。治疗后，两组患者腹痛、腹泻情况均明显好转，其中观察组腹痛、腹泻情况明显优于对照组，P〈0．05。结果表明，与单纯中西药口服相比，中西药口服联合保留灌肠治疗UC疗效更佳，值得临床推广应用。

In order to explore the clinical effect of Chinese herb and western medicine for oral administra- tion and for retention enema in the treatment of ulcerative colitis（UC）,author retrospectively analyzed and compared the curative effect of observation group（ n =38） and control group（ n =30） which observation group received this integration of oral adminitration and retention enema with Chinese herb and western medicine,while control group only received oral administration of Chinese herb and western medicine. As results,in observation group 12 cases were cured, 18 of excellent response, 7 of response, 1 of non-response and total effective rate was 97.4 % （37/38） ; while, in control group, 8,12,6,4 and 86.7 %（26/30）, respec- tively;apparently, the effective rate of observation group was significantly higher than that of control group （ P 〈0.05）;after treatment the abdomenal pain and diarrhea of both group＇s patients were greatly im- proved,but in improvement of symptoms observation group significantly superior to control group（ P 〈0.05）.Results show that compared with alone oral adminitration the integration of oral adminitration and retention enema for UC has more better effect,and it is worthy to be popularized to use clinically.